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Titel:

Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke.

Dokumenttyp:
Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial
Autor(en):
Sacco, RL; Diener, HC; Yusuf, S; Cotton, D; Ounpuu, S; Lawton, WA; Palesch, Y; Martin, RH; Albers, GW; Bath, P; Bornstein, N; Chan, BP; Chen, ST; Cunha, L; Dahlof, B; De Keyser, J; Donnan, GA; Estol, C; Gorelick, P; Gu, V; Hermansson, K; Hilbrich, L; Kaste, M; Lu, C; Machnig, T; Pais, P; Roberts, R; Skvortsova, V; Teal, P; Toni, D; VanderMaelen, C; Voigt, T; Weber, M; Yoon, BW
Abstract:
BACKGROUND: Recurrent stroke is a frequent, disabling event after ischemic stroke. This study compared the efficacy and safety of two antiplatelet regimens--aspirin plus extended-release dipyridamole (ASA-ERDP) versus clopidogrel. METHODS: In this double-blind, 2-by-2 factorial trial, we randomly assigned patients to receive 25 mg of aspirin plus 200 mg of extended-release dipyridamole twice daily or to receive 75 mg of clopidogrel daily. The primary outcome was first recurrence of stroke. The s...     »
Zeitschriftentitel:
N Engl J Med
Jahr:
2008
Band / Volume:
359
Heft / Issue:
12
Seitenangaben Beitrag:
1238-51
Sprache:
eng
Volltext / DOI:
doi:10.1056/NEJMoa0805002
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18753638
Print-ISSN:
0028-4793
TUM Einrichtung:
Neurologische Klinik und Poliklinik
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