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Titel:

Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFE

Dokumenttyp:
Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Autor(en):
Diener, HC; Sacco, RL; Yusuf, S; Cotton, D; Ounpuu, S; Lawton, WA; Palesch, Y; Martin, RH; Albers, GW; Bath, P; Bornstein, N; Chan, BP; Chen, ST; Cunha, L; Dahlof, B; De Keyser, J; Donnan, GA; Estol, C; Gorelick, P; Gu, V; Hermansson, K; Hilbrich, L; Kaste, M; Lu, C; Machnig, T; Pais, P; Roberts, R; Skvortsova, V; Teal, P; Toni, D; VanderMaelen, C; Voigt, T; Weber, M; Yoon, BW
Abstract:
BACKGROUND: The treatment of ischaemic stroke with neuroprotective drugs has been unsuccessful, and whether these compounds can be used to reduce disability after recurrent stroke is unknown. The putative neuroprotective effects of antiplatelet compounds and the angiotensin II receptor antagonist telmisartan were investigated in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial. METHODS: Patients who had had an ischaemic stroke were randomly assigned in a two by two...     »
Zeitschriftentitel:
Lancet Neurol
Jahr:
2008
Band / Volume:
7
Heft / Issue:
10
Seitenangaben Beitrag:
875-84
Sprache:
eng
Volltext / DOI:
doi:10.1016/S1474-4422(08)70198-4
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18757238
Print-ISSN:
1474-4422
TUM Einrichtung:
Neurologische Klinik und Poliklinik
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