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Title:

A complex pattern of chemokine receptor expression is seen in osteosarcoma.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
von Luettichau, I; Segerer, S; Wechselberger, A; Notohamiprodjo, M; Nathrath, M; Kremer, M; Henger, A; Djafarzadeh, R; Burdach, S; Huss, R; Nelson, PJ
Abstract:
BACKGROUND: Osteosarcoma is the most frequent bone tumor in childhood and adolescence. Patients with primary metastatic disease have a poor prognosis. It is therefore important to better characterize the biology of this tumor to define new prognostic markers or therapeutic targets for tailored therapy. Chemokines and their receptors have been shown to be involved in the development and progression of malignant tumors. They are thought to be active participants in the biology of osteosarcoma. The...     »
Journal title abbreviation:
BMC Cancer
Year:
2008
Journal volume:
8
Pages contribution:
23
Language:
eng
Fulltext / DOI:
doi:10.1186/1471-2407-8-23
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18215331
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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