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Title:

Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Lange, M; Kaynak, B; Forster, UB; Tönjes, M; Fischer, JJ; Grimm, C; Schlesinger, J; Just, S; Dunkel, I; Krueger, T; Mebus, S; Lehrach, H; Lurz, R; Gobom, J; Rottbauer, W; Abdelilah-Seyfried, S; Sperling, S
Abstract:
Chromatin remodeling and histone modifications facilitate access of transcription factors to DNA by promoting the unwinding and destabilization of histone-DNA interactions. We present DPF3, a new epigenetic key factor for heart and muscle development characterized by a double PHD finger. DPF3 is associated with the BAF chromatin remodeling complex and binds methylated and acetylated lysine residues of histone 3 and 4. Thus, DPF3 may represent the first plant homeodomains that bind acetylated lys...     »
Journal title abbreviation:
Genes Dev
Year:
2008
Journal volume:
22
Journal issue:
17
Pages contribution:
2370-84
Language:
eng
Fulltext / DOI:
doi:10.1101/gad.471408
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18765789
Print-ISSN:
0890-9369
TUM Institution:
Klinik für Kinderkardiologie und angeborene Herzfehler (Prof. Hess)
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