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Titel:

Weekly docetaxel monotherapy for advanced gastric or esophagogastric junction cancer Results of a phase II study in elderly patients or patients with impaired performance status.

Dokumenttyp:
Journal Article; Review
Autor(en):
Abbrederis, K; Lorenzen, S; von Weikersthal, LF; Vehling-Kaiser, U; Schuster, T; Rothling, N; Peschel, C; Lordick, F
Abstract:
BACKGROUND: Three-weekly docetaxel is active in patients with advanced esophagogastric cancer but myelosuppression may make this schedule unsuitable for some patient groups such as elderly, pretreated, or poor performance status patients. PATIENTS AND METHODS: Eligible patients were chemonaive with Karnofsky index /=70 years) included, 87% had Karnofsky index /=100 days (disease stabilization rate: 36%). Overall response rate was 9%; median overall survival was 7.0 months. CONCLUSIONS: Weekly d...     »
Zeitschriftentitel:
Crit Rev Oncol Hematol
Jahr:
2008
Band / Volume:
66
Heft / Issue:
1
Seitenangaben Beitrag:
84-90
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.critrevonc.2007.12.001
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18243012
Print-ISSN:
1040-8428
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie); Institut für Medizinische Statistik und Epidemiologie
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