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Titel:

Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Gieger, C; Geistlinger, L; Altmaier, E; Hrabé de Angelis, M; Kronenberg, F; Meitinger, T; Mewes, HW; Wichmann, HE; Weinberger, KM; Adamski, J; Illig, T; Suhre, K
Abstract:
The rapidly evolving field of metabolomics aims at a comprehensive measurement of ideally all endogenous metabolites in a cell or body fluid. It thereby provides a functional readout of the physiological state of the human body. Genetic variants that associate with changes in the homeostasis of key lipids, carbohydrates, or amino acids are not only expected to display much larger effect sizes due to their direct involvement in metabolite conversion modification, but should also provide access to...     »
Zeitschriftentitel:
PLoS Genet
Jahr:
2008
Band / Volume:
4
Heft / Issue:
11
Seitenangaben Beitrag:
e1000282
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pgen.1000282
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19043545
Print-ISSN:
1553-7390
TUM Einrichtung:
Institut für Humangenetik
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