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Title:

Lack of association between the MEF2A gene and myocardial infarction.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Lieb, W; Mayer, B; König, IR; Borwitzky, I; Götz, A; Kain, S; Hengstenberg, C; Linsel-Nitschke, P; Fischer, M; Döring, A; Wichmann, HE; Meitinger, T; Kreutz, R; Ziegler, A; Schunkert, H; Erdmann, J
Abstract:
BACKGROUND: Coronary artery disease (CAD) and myocardial infarction (MI) are caused in part by genetic factors. Recently, the MEF2A gene was linked to MI/CAD in a single pedigree with autosomal-dominant pattern of inheritance. In addition, genetic variants within the gene have been associated with MI in case-control settings, producing inconsistent results. METHODS AND RESULTS: The MEF2A gene was sequenced in MI patients from 23 MI families (> or =5 affected members per family), but no mutation...     »
Journal title abbreviation:
Circulation
Year:
2008
Journal volume:
117
Journal issue:
2
Pages contribution:
185-91
Language:
eng
Fulltext / DOI:
doi:10.1161/CIRCULATIONAHA.107.728485
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18086930
Print-ISSN:
0009-7322
TUM Institution:
Else Kröner-Fresenius-Zentrum für Ernährungsmedizin - Klinik für Ernährungsmedizin; Institut für Humangenetik
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