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Title:

Nuclear localization and cytosolic overexpression of LASP-1 correlates with tumor size and nodal-positivity of human breast carcinoma.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Grunewald, TG; Kämmerer, U; Kapp, M; Eck, M; Dietl, J; Butt, E; Honig, A
Abstract:
BACKGROUND: LIM and SH3 protein 1 (LASP-1), initially identified from human breast cancer, is a specific focal adhesion protein involved in cell proliferation and migration, which was reported to be overexpressed in 8-12 % of human breast cancers and thought to be exclusively located in cytoplasm. METHODS: In the present work we analyzed the cellular and histological expression pattern of LASP-1 and its involvement in biological behavior of human breast cancer through correlation with standard c...     »
Journal title abbreviation:
BMC Cancer
Year:
2007
Journal volume:
7
Pages contribution:
198
Language:
eng
Fulltext / DOI:
doi:10.1186/1471-2407-7-198
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17956604
TUM Institution:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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