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Title:

HIV-induced changes in T cell signaling pathways.

Document type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Author(s):
Schweneker, M; Favre, D; Martin, JN; Deeks, SG; McCune, JM
Abstract:
Infection with HIV usually results in chronic activation of the immune system, with profound quantitative and qualitative changes in the T cell compartment. To better understand the mechanistic basis for T cell dysfunction and to discern whether such mechanisms are reversed after effective antiviral treatment, we analyzed changes in signaling pathways of human CD4(+) and CD8(+) T cells from 57 HIV-infected subjects in varying stages of disease progression and treatment, including long-term nonpr...     »
Journal title abbreviation:
J Immunol
Year:
2008
Journal volume:
180
Journal issue:
10
Pages contribution:
6490-500
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18453567
Print-ISSN:
0022-1767
TUM Institution:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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