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Titel:

Subcellular distribution of inorganic and methylated arsenic compounds in human urothelial cells and human hepatocytes.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Dopp, E; von Recklinghausen, U; Hartmann, LM; Stueckradt, I; Pollok, I; Rabieh, S; Hao, L; Nüssler, A; Katier, C; Hirner, AV; Rettenmeier, AW
Abstract:
Epidemiological studies have indicated that exposure of humans to inorganic arsenic in drinking water is associated with the occurrence of bladder cancer. The mechanisms by which arsenic induces this malignancy are still uncertain; however, arsenic metabolites are suspected to play a pivotal role. The aim of the present study was the investigation of uptake capabilities of human urothelial cells (UROtsa) compared with primary human hepatocytes (phH) as well as the intracellular distribution of...     »
Zeitschriftentitel:
Drug Metab Dispos
Jahr:
2008
Band / Volume:
36
Heft / Issue:
5
Seitenangaben Beitrag:
971-9
Volltext / DOI:
doi:10.1124/dmd.107.019034
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18256204
Print-ISSN:
0090-9556
TUM Einrichtung:
Klinik und Poliklinik für Unfallchirurgie
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