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Title:

NKG2D-dependent effector function of bronchial epithelium-activated alloreactive T-cells.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Kraetzel, K; Stoelcker, B; Eissner, G; Multhoff, G; Pfeifer, M; Holler, E; Schulz, C
Abstract:
Allogeneic haematopoietic stem cell transplantation (SCT) has emerged as a curative therapeutic option. However, the role of graft-versus-host disease in lung injury after SCT has yet to be determined. In the present study, primary bronchial epithelial cells and the bronchial epithelial cell line BEAS-2B were used to investigate immune responses of allogeneic CD8+ T-cells directed against respiratory epithelial cells. Following stimulation with irradiated bronchial epithelial cells, CD8+ T-cells...     »
Journal title abbreviation:
Eur Respir J
Year:
2008
Journal volume:
32
Journal issue:
3
Pages contribution:
563-70
Language:
eng
Fulltext / DOI:
doi:10.1183/09031936.00096407
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18417514
Print-ISSN:
0903-1936
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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