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Titel:

Prothrombinase-induced clotting time assay for determination of the anticoagulant effects of unfractionated and low-molecular-weight heparins, fondaparinux, and thrombin inhibitors.

Dokumenttyp:
Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Calatzis, A; Peetz, D; Haas, S; Spannagl, M; Rudin, K; Wilmer, M
Abstract:
The prothrombinase-induced clotting time assay (PiCT, Pentapharm, Basel, Switzerland) is a clotting assay sensitive to factor Xa and factor IIa inhibitors. It is based on the addition of factor Xa and snake venom RVV-V (Russell viper venom factor V activator) specifically activating factor V and phospholipids to platelet-poor plasma. Following an incubation time, the mixture is recalcified and the clotting time is determined. An almost linear dose-response and high sensitivity of the assay for u...     »
Zeitschriftentitel:
Am J Clin Pathol
Jahr:
2008
Band / Volume:
130
Heft / Issue:
3
Seitenangaben Beitrag:
446-54
Sprache:
eng
Volltext / DOI:
doi:10.1309/Q0G21Y26UR0UHQ1A
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18701419
Print-ISSN:
0002-9173
TUM Einrichtung:
Institut für Experimentelle Onkologie und Therapieforschung
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