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Title:

New anti-infective coatings of medical implants.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Matl, FD; Obermeier, A; Repmann, S; Friess, W; Stemberger, A; Kuehn, KD
Abstract:
Implantable devices are highly susceptible to infection and are therefore a major risk in surgery. The present work presents a novel strategy to prevent the formation of a biofilm on polytetrafluoroethylene (PTFE) grafts. PTFE grafts were coated with gentamicin and teicoplanin incorporated into different lipid-like carriers under aseptic conditions in a dipping process. Poly-d,l-lactic acid, tocopherol acetate, the diglyceride Softisan 649, and the triglyceride Dynasan 118 were used as drug carr...     »
Journal title abbreviation:
Antimicrob Agents Chemother
Year:
2008
Journal volume:
52
Journal issue:
6
Pages contribution:
1957-63
Language:
eng
Fulltext / DOI:
doi:10.1128/AAC.01438-07
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18362194
Print-ISSN:
0066-4804
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung
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