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Titel:

Aerosol gene delivery to the murine lung is mouse strain dependent.

Dokumenttyp:
Journal Article
Autor(en):
Dames, P; Ortiz, A; Schillinger, U; Lesina, E; Plank, C; Rosenecker, J; Rudolph, C
Abstract:
The cationic polymer polyethylenimine (PEI) has been previously demonstrated to efficiently deliver genes to the lungs of mice in vivo via nebulization. Although within these studies various mouse strains were used in individual experiments, no direct comparison of gene delivery to different mouse strains via aerosol application has been published to date. With respect to the widespread use of mice as animal models of inherited and acquired diseases, such data could be of relevance to select the...     »
Zeitschriftentitel:
J Mol Med
Jahr:
2007
Band / Volume:
85
Heft / Issue:
4
Seitenangaben Beitrag:
371-8
Sprache:
eng
Volltext / DOI:
doi:10.1007/s00109-006-0130-9
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/17160403
Print-ISSN:
0946-2716
TUM Einrichtung:
Institut für Experimentelle Onkologie und Therapieforschung
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