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Titel:

Selective changes of resting-state networks in individuals at risk for Alzheimer's disease.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Sorg, C; Riedl, V; Muhlau, M; Calhoun, VD; Eichele, T; Läer, L; Drzezga, A; Förstl, H; Kurz, A; Zimmer, C; Wohlschläger, AM
Abstract:
Alzheimer's disease (AD) is a neurodegenerative disorder that prominently affects cerebral connectivity. Assessing the functional connectivity at rest, recent functional MRI (fMRI) studies reported on the existence of resting-state networks (RSNs). RSNs are characterized by spatially coherent, spontaneous fluctuations in the blood oxygen level-dependent signal and are made up of regional patterns commonly involved in functions such as sensory, attention, or default mode processing. In AD, the de...     »
Zeitschriftentitel:
Proc Natl Acad Sci U S A
Jahr:
2007
Band / Volume:
104
Heft / Issue:
47
Seitenangaben Beitrag:
18760-5
Sprache:
eng
Volltext / DOI:
doi:10.1073/pnas.0708803104
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18003904
Print-ISSN:
0027-8424
TUM Einrichtung:
Fachgebiet Neuroradiologie (Prof. Zimmer); Klinik und Poliklinik für Nuklearmedizin; Klinik und Poliklinik für Psychiatrie und Psychotherapie; Neurologische Klinik und Poliklinik
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