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Titel:

Cytochrome P450 activity mirrors nitric oxide levels in postoperative sepsis: predictive indicators of lethal outcome.

Dokumenttyp:
Journal Article; Article
Autor(en):
Novotny, AR; Emmanuel, K; Maier, S; Westerholt, A; Weighardt, H; Stadler, J; Bartels, H; Schwaiger, M; Siewert, JR; Holzmann, B; Heidecke, CD
Abstract:
BACKGROUND: The development of liver failure significantly influences prognosis during the course of major septic complications. Although the underlying cause for septic liver failure is still unclear, research using animal models has demonstrated that an increased nitric oxide (NO) synthesis compromises detoxification processes in the liver. METHODS: In the present study, serum NO levels were measured by high-performance liquid chromatography (HPLC) and aminopyrine breath test (ABT) scores, ref...     »
Zeitschriftentitel:
Surgery
Jahr:
2007
Band / Volume:
141
Heft / Issue:
3
Seitenangaben Beitrag:
376-84
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.surg.2006.08.011
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/17349850
Print-ISSN:
0039-6060
TUM Einrichtung:
Chirurgische Klinik und Poliklinik; Klinik und Poliklinik für Nuklearmedizin
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