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Titel:

Molecular coronary MR imaging of human thrombi using EP-2104R, a fibrin-targeted contrast agent: experimental study in a swine model.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Spuentrup, E; Katoh, M; Wiethoff, AJ; Buecker, A; Botnar, RM; Parsons, EC; Guenther, RW
Abstract:
PURPOSE: The aim of this study was to investigate the use of a fibrin-specific contrast agent (EP-2104R, EPIX Pharmaceuticals, Lexington, Massachusetts, USA) for targeted molecular magnetic resonance (MR) imaging of human clot material removed from patients in a model of coronary thrombosis in swine. MATERIALS AND METHODS: Freshly ex vivo engineered clots from human blood and human in situ developed clots removed from patients were delivered into the coronary arteries of nine domestic swine. For...     »
Zeitschriftentitel:
Rofo
Jahr:
2007
Band / Volume:
179
Heft / Issue:
11
Seitenangaben Beitrag:
1166-73
Sprache:
eng
Volltext / DOI:
doi:10.1055/s-2007-963573
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/17948194
Print-ISSN:
1438-9029
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin
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