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Title:

Clinical evaluation of experimentally induced choroidal neovascularizations in pigmented rabbits by subretinal injection of lipid hydroperoxide and consecutive preliminary photodynamic treatment with Tookad.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Framme, C; Sachs, HG; Kobuch, K; Flucke, B; Birngruber, R
Abstract:
PURPOSE: Up to date several approaches have been undertaken to achieve an 'easy-to-handle' animal model of choroidal neovascularizations (CNVs) in rabbits; however, so far in none of the studies could healthy retinal tissue be maintained, which is mandatory to further investigate the effects of photodynamic therapy (PDT) or anti-vascular-endothelial-growth-factor treatments. It was our aim to reevaluate and verify the method of inducing experimental CNVs in rabbits using subretinally injected l...     »
Journal title abbreviation:
Ophthalmologica
Year:
2008
Journal volume:
222
Journal issue:
4
Pages contribution:
254-64
Language:
eng
Fulltext / DOI:
doi:10.1159/000136903
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18525218
Print-ISSN:
0030-3755
TUM Institution:
Klinik und Poliklinik für Augenheilkunde
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