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Title:

Multiple testing for SNP-SNP interactions.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Boulesteix, AL; Strobl, C; Weidinger, S; Wichmann, HE; Wagenpfeil, S
Abstract:
Most genetic diseases are complex, i.e. associated to combinations of SNPs rather than individual SNPs. In the last few years, this topic has often been addressed in terms of SNP-SNP interaction patterns given as expressions linked by logical operators. Methods for multiple testing in high-dimensional settings can be applied when many SNPs are considered simultaneously. However, another less well-known multiple testing problem arises within a fixed subset of SNPs when the logic expression is cho...     »
Journal title abbreviation:
Stat Appl Genet Mol Biol
Year:
2007
Journal volume:
6
Pages contribution:
Article37
Language:
eng
Fulltext / DOI:
doi:10.2202/1544-6115.1315
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18171321
Print-ISSN:
2194-6302
TUM Institution:
Institut für Medizinische Statistik und Epidemiologie; Klinik und Poliklinik für Dermatologie und Allergologie
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