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Title:

Significant changes in circulating plasma levels of IGF1 and IGFBP3 after conventional or dose-intensified adjuvant treatment of breast cancer patients with one to three positive lymph nodes.

Document type:
Journal Article
Author(s):
Kümmel, S; Eggemann, H; Luftner, D; Gebauer, N; Bühler, H; Schaller, G; Schmid, P; Kreienberg, R; Emons, G; Kriner, M; Elling, D; Blohmer, JU; Thomas, A
Abstract:
The insulin-like growth factor 1 (IGF1) and its binding protein IGFBP3 (insulin-like growth factor binding protein 3) play a pivotal role during the growth and development of tissues. The purpose of this study was to evaluate the influence of anthracycline- and taxane-containing adjuvant chemotherapy in breast cancer patients on the circulating plasma levels of IGF1 and its main binding protein, IGFBP3. This investigation was part of a prospective randomized phase III study in which breast cance...     »
Journal title abbreviation:
Int J Biol Markers
Year:
2007
Journal volume:
22
Journal issue:
3
Pages contribution:
186-93
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17922461
Print-ISSN:
0393-6155
TUM Institution:
Institut für Medizinische Statistik und Epidemiologie
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