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Title:

Imaging Human Cerebral Pain Modulation by Dose-dependent Opioid Analgesia: A Positron Emission Tomography Activation Study Using Remifentanil.

Document type:
Journal Article; Article
Author(s):
Wagner, KJ; Sprenger, T; Kochs, EF; Tölle, TR; Valet, M; Willoch, F
Abstract:
BACKGROUND:: Previous imaging studies have demonstrated a number of cortical and subcortical brain structures to be activated during noxious stimulation and infusion of narcotic analgesics. This study used O-water and positron emission tomography to investigate dose-dependent effects of the short-acting mu-selective opioid agonist remifentanil on regional cerebral blood flow during experimentally induced painful heat stimulation in healthy male volunteers. METHODS:: Positron emission tomography...     »
Journal title abbreviation:
Anesthesiology
Year:
2007
Journal volume:
106
Journal issue:
3
Pages contribution:
548-556
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17325514
Print-ISSN:
0003-3022
TUM Institution:
Klinik für Anästhesiologie (DHM); Neurologische Klinik und Poliklinik
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