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Document type:
Clinical Trial; Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Article
Author(s):
Reck, M; von Pawel, J; Macha, HN; Kaukel, E; Deppermann, KM; Bonnet, R; Ulm, K; Hessler, S; Gatzemeier, U
Title:
Randomized phase III trial of paclitaxel, etoposide, and carboplatin versus carboplatin, etoposide, and vincristine in patients with small-cell lung cancer.
Abstract:
BACKGROUND: Paclitaxel administered in combination with a topoisomerase-II inhibitor (such as etoposide) and carboplatin is an effective and safe first-line treatment for patients with small-cell lung cancer (SCLC). We conducted a randomized phase III multicenter trial to determine whether paclitaxel plus etoposide plus carboplatin improves the outcome of patients with primary SCLC relative to standard chemotherapy (carboplatin, etoposide, and vincristine). METHODS: Between January 1998 and Dece...     »
Journal title abbreviation:
J Natl Cancer Inst
Year:
2003
Journal volume:
95
Journal issue:
15
Pages contribution:
1118-27
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/12902441
Print-ISSN:
0027-8874
TUM Institution:
Institut für Medizinische Statistik und Epidemiologie
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