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Titel:

Serological profiling of the EBV immune response in Chronic Fatigue Syndrome using a peptide microarray.

Dokumenttyp:
Journal Article; Article
Autor(en):
Loebel, Madlen; Eckey, Maren; Sotzny, Franziska; Hahn, Elisabeth; Bauer, Sandra; Grabowski, Patricia; Zerweck, Johannes; Holenya, Pavlo; Hanitsch, Leif G; Wittke, Kirsten; Borchmann, Peter; Rüffer, Jens-Ulrich; Hiepe, Falk; Ruprecht, Klemens; Behrends, Uta; Meindl, Carola; Volk, Hans-Dieter; Reimer, Ulf; Scheibenbogen, Carmen
Abstract:
Epstein-Barr-Virus (EBV) plays an important role as trigger or cofactor for various autoimmune diseases. In a subset of patients with Chronic Fatigue Syndrome (CFS) disease starts with infectious mononucleosis as late primary EBV-infection, whereby altered levels of EBV-specific antibodies can be observed in another subset of patients.We performed a comprehensive mapping of the IgG response against EBV comparing 50 healthy controls with 92 CFS patients using a microarray platform. Patients with...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2017
Band / Volume:
12
Heft / Issue:
6
Seitenangaben Beitrag:
e0179124
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0179124
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28604802
Print-ISSN:
1932-6203
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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