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Title:

Importance of molecular pathology in obstetrics-Placenta in the spotlight

Document type:
Article
Author(s):
Karge, Anne; Enzensberger, Christian; Stickeler, Elmar; Maurer, Jochen; Kuschel, Bettina; Pecks, Ulrich; Graupner, Oliver
Abstract:
Background Molecular pathways play an important role in the pathogenesis and clinical manifestation of placenta-associated diseases, such as preeclampsia (PE) or fetal growth restriction (FGR). Due to an impaired placentation resulting in a disturbed remodeling of the uterine spiral arteries and placental insufficiency, the humoral immune response causes the release or upregulation and downregulation of (anti)angiogenic proteins, microRNA originating from syncytiotrophoblasts, and interleukins....     »
Journal title abbreviation:
Gynakologie
Year:
2023
Journal volume:
56
Journal issue:
3
Pages contribution:
191-199
Fulltext / DOI:
doi:10.1007/s00129-023-05054-4
Print-ISSN:
2731-7102
TUM Institution:
Klinik und Poliklinik für Frauenheilkunde (Prof. Kiechle)
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