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Title:

Human Glioma Migration and Infiltration Properties as a Target for Personalized Radiation Medicine.

Document type:
Journal Article; Review
Author(s):
Wank, Michaela; Schilling, Daniela; Schmid, Thomas E; Meyer, Bernhard; Gempt, Jens; Barz, Melanie; Schlegel, Jürgen; Liesche, Friederike; Kessel, Kerstin A; Wiestler, Benedikt; Bette, Stefanie; Zimmer, Claus; Combs, Stephanie E
Abstract:
Gliomas are primary brain tumors that present the majority of malignant adult brain tumors. Gliomas are subdivided into low- and high-grade tumors. Despite extensive research in recent years, the prognosis of malignant glioma patients remains poor. This is caused by naturally highly infiltrative capacities as well as high levels of radio- and chemoresistance. Additionally, it was shown that low linear energy transfer (LET) irradiation enhances migration and invasion of several glioma entities wh...     »
Journal title abbreviation:
Cancers (Basel)
Year:
2018
Journal volume:
10
Journal issue:
11
Language:
eng
Fulltext / DOI:
doi:10.3390/cancers10110456
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30463322
TUM Institution:
Fachgebiet Neuroradiologie (Prof. Zimmer); Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für RadioOnkologie und Strahlentherapie; Neurochirurgische Klinik und Poliklinik
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