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Titel:

Impact of expansion and redifferentiation under hypothermia on chondrogenic capacity of cultured human septal chondrocytes.

Dokumenttyp:
Journal Article
Autor(en):
von Bomhard, Achim; Faust, Joseph; Elsaesser, Alexander F; Schwarz, Silke; Pippich, Katharina; Rotter, Nicole
Abstract:
A critical limitation in the cultivation of cartilage for tissue engineering is the dedifferentiation in chondrocytes, mainly during in vitro amplification. Despite many previous studies investigating the influence of various conditions, no data exist concerning the effects of hypothermia. Our aim has been to influence chondrocyte dedifferentiation in vitro by hypothermic conditions. Chondrocytes were isolated from cartilage biopsies and seeded in monolayer and in three-dimensional pellet-cultur...     »
Zeitschriftentitel:
J Tissue Eng
Jahr:
2017
Band / Volume:
8
Seitenangaben Beitrag:
2041731417732655
Sprache:
eng
Volltext / DOI:
doi:10.1177/2041731417732655
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29051809
TUM Einrichtung:
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
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