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Titel:

Myocardial infarction accelerates breast cancer via innate immune reprogramming.

Dokumenttyp:
Article; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Autor(en):
Koelwyn, Graeme J; Newman, Alexandra A C; Afonso, Milessa S; van Solingen, Coen; Corr, Emma M; Brown, Emily J; Albers, Kathleen B; Yamaguchi, Naoko; Narke, Deven; Schlegel, Martin; Sharma, Monika; Shanley, Lianne C; Barrett, Tessa J; Rahman, Karishma; Mezzano, Valeria; Fisher, Edward A; Park, David S; Newman, Jonathan D; Quail, Daniela F; Nelson, Erik R; Caan, Bette J; Jones, Lee W; Moore, Kathryn J
Abstract:
Disruption of systemic homeostasis by either chronic or acute stressors, such as obesity1 or surgery2, alters cancer pathogenesis. Patients with cancer, particularly those with breast cancer, can be at increased risk of cardiovascular disease due to treatment toxicity and changes in lifestyle behaviors3-5. While elevated risk and incidence of cardiovascular events in breast cancer is well established, whether such events impact cancer pathogenesis is not known. Here we show that myocardial infar...     »
Zeitschriftentitel:
Nat Med
Jahr:
2020
Band / Volume:
26
Heft / Issue:
9
Seitenangaben Beitrag:
1452-1458
Volltext / DOI:
doi:10.1038/s41591-020-0964-7
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32661390
Print-ISSN:
1078-8956
TUM Einrichtung:
Klinik für Anästhesiologie (DHM)
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