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Titel:

Aggrecan: a new biomarker for acute type A aortic dissection.

Dokumenttyp:
Journal Article
Autor(en):
König, Karl C; Lahm, Harald; Dreßen, Martina; Doppler, Stefanie A; Eichhorn, Stefan; Beck, Nicole; Kraehschuetz, Kathrin; Doll, Sophia; Holdenrieder, Stefan; Kastrati, Adnan; Lange, Rüdiger; Krane, Markus
Abstract:
Acute type A aortic dissection (ATAAD) constitutes a life-threatening aortic pathology with significant morbidity and mortality. Without surgical intervention the usual mortality rate averages between 1 and 2% per hour. Thus, an early diagnosis of ATAAD is of pivotal importance to direct the affected patients to the appropriate treatment. Preceding tests to find an appropriate biomarker showed among others an increased aggrecan (ACAN) mRNA expression in aortic tissue of ATAAD patients. As a cons...     »
Zeitschriftentitel:
Sci Rep
Jahr:
2021
Band / Volume:
11
Heft / Issue:
1
Volltext / DOI:
doi:10.1038/s41598-021-89653-y
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33990642
Print-ISSN:
2045-2322
TUM Einrichtung:
Institut für Laboratoriumsmedizin (keine SAP-Zuordnung!); Klinik für Herz- und Gefäßchirurgie (Prof. Lange); Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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