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Title:

Prospective assessment of short- and long-term quality of life after ablation for atrial fibrillation.

Document type:
Journal Article; Article
Author(s):
Fichtner, S; Deisenhofer, I; Kindsmüller, S; Dzijan-Horn, M; Tzeis, S; Reents, T; Wu, J; Luise Estner, H; Jilek, C; Ammar, S; Kathan, S; Hessling, G; Ladwig, KH
Abstract:
Quality of Life After Ablation for Atrial Fibrillation. Background : This study prospectively assesses different aspects of short- and long-term quality of life (QoL) after catheter ablation for atrial fibrillation (AF). An analysis of 7 validated generic and tailored questionnaires was performed with regard to the relation of QoL to ablation success. Methods : The study included 133 patients (74% men, age 57±10) who underwent pulmonary vein isolation ± linear or electrogram-guided substrate modification for AF. QoL was quantitatively assessed at baseline, 3 months after ablation and at a median of 4.3 ± 0.5 years after ablation by the AF severity scale (AFSS), AF symptom checklist (AFSC), WHO-5-Well-Being-Index (WHO), Major Depression Inventory (MDI), Sleep and Vegetative disorder (SV), Vital Exhaustion (VE), and Illness intrusiveness (Ii). Results: QoL was improved significantly 3 months after ablation in all patients (regardless of ablation success or AF type) and stayed significantly improved after a median of 4.3±0.5 years (AFSS, AFSC, WHO, MDI, VE, PE (all P < 0.001), and SV (P = 0.007)). Patients who had a successful ablation improved significantly more than patients with an unsuccessful ablation in the AFSS, AFSC, and MDI questionnaire (delta change from baseline to long-term follow-up P = <0.001, P = <0.001, and P = 0.039, respectively). Conclusion: Overall, all patients significantly improved their QoL irrespective of the AF type in all questionnaires 3 months and 4 years after ablation. The increase in QoL was significantly greater in patients who underwent a successful ablation than patients with unsuccessful ablation in the AFSS, AFSC, and MDI questionnaire. Cardiovasc Electrophysiol, Vol. 23, pp. 121-127, February 2012).
Journal title abbreviation:
J Cardiovasc Electrophysiol
Year:
2012
Journal volume:
23
Journal issue:
2
Pages contribution:
121-7
Language:
eng
Fulltext / DOI:
doi:10.1111/j.1540-8167.2011.02165.x
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21914021
Print-ISSN:
1045-3873
TUM Institution:
I. Medizinische Klinik und Poliklinik (Kardiologie); Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert); Klinik für Kinderkardiologie und angeborene Herzfehler (Prof. Hess); Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie
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