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Title:

Functionalization of CoCr surfaces with cell adhesive peptides to promote HUVECs adhesion and proliferation

Document type:
Article
Author(s):
Castellanos, MI; Mas-Moruno, C; Grau, A; Serra-Picamal, X; Trepat, X; Albericio, F; Joner, M; Gil, FJ; Ginebra, MP; Manero, JM; Pegueroles, M
Abstract:
Biomimetic surface modification with peptides that have specific cell-binding moieties is a promising approach to improve endothelialization of metal-based stents. In this study, we functionalized CoCr surfaces with RGDS, REDV, YIGSR peptides and their combinations to promote endothelial cells (ECs) adhesion and proliferation. An extensive characterization of the functionalized surfaces was performed by XPS analysis, surface charge and quartz crystal microbalance with dissipation monitoring (QCM...     »
Journal title abbreviation:
Appl Surf Sci
Year:
2017
Journal volume:
393
Pages contribution:
82-92
Language:
eng
Print-ISSN:
0169-4332
TUM Institution:
Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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