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Title:

Psoriasis Pathogenesis: Keratinocytes Are Back in the Spotlight.

Document type:
Journal Article; Comment
Author(s):
Garzorz-Stark, Natalie; Eyerich, Kilian
Abstract:
Psoriasis is a T helper type 17-mediated immune disease. Initial triggers that lead to T helper type 17 production and inflammatory cell recruitment into skin are being delineated. Autoantigens that stimulate T helper type 17 cells are also being identified. A new and important piece of the puzzle indicates that keratinocytes not only amplify inflammation, but that they are essential for a full-blown IL-17-mediated psoriatic phenotype in mice.
Journal title abbreviation:
J Invest Dermatol
Year:
2019
Journal volume:
139
Journal issue:
5
Pages contribution:
995-996
Fulltext / DOI:
doi:10.1016/j.jid.2019.01.026
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31010530
Print-ISSN:
0022-202X
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie; Professur für Experimentelle Dermato-Immunologie (Prof. Eyerich)
 BibTeX