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- Title:
Psoriasis Pathogenesis: Keratinocytes Are Back in the Spotlight.
- Document type:
- Journal Article; Comment
- Author(s):
- Garzorz-Stark, Natalie; Eyerich, Kilian
- Abstract:
- Psoriasis is a T helper type 17-mediated immune disease. Initial triggers that lead to T helper type 17 production and inflammatory cell recruitment into skin are being delineated. Autoantigens that stimulate T helper type 17 cells are also being identified. A new and important piece of the puzzle indicates that keratinocytes not only amplify inflammation, but that they are essential for a full-blown IL-17-mediated psoriatic phenotype in mice.
- Journal title abbreviation:
- J Invest Dermatol
- Year:
- 2019
- Journal volume:
- 139
- Journal issue:
- 5
- Pages contribution:
- 995-996
- Fulltext / DOI:
- doi:10.1016/j.jid.2019.01.026
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/31010530
- Print-ISSN:
- 0022-202X
- TUM Institution:
- Klinik und Poliklinik für Dermatologie und Allergologie; Professur für Experimentelle Dermato-Immunologie (Prof. Eyerich)
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