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Titel:

Modulation of Lymphangiogenesis in Incisional Murine Diabetic Wound Healing Using Negative Pressure Wound Therapy.

Dokumenttyp:
Journal Article
Autor(en):
Wu, Mengfan; Matar, Dany Y; Yu, Zhen; Chen, Ziyu; Knoedler, Samuel; Ng, Brian; Darwish, Oliver; Haug, Valentin; Friedman, Leigh; Orgill, Dennis P; Panayi, Adriana C
Abstract:
Objective: Despite the significant function of lymphatics in wound healing, and frequent clinical use of Negative Pressure Wound Therapy (NPWT), the effect of mechanical force application on lymphangiogenesis remains to be elucidated. We utilize a murine incisional wound healing model to assess the mechanisms of lymphangiogenesis following NPWT. Approach: Dorsal incisional skin wounds were created on diabetic mice (genetically obese leptin receptor-deficient mice [db/db]; n = 30) and covered wi...     »
Zeitschriftentitel:
Adv Wound Care (New Rochelle)
Jahr:
2023
Band / Volume:
12
Heft / Issue:
9
Seitenangaben Beitrag:
483-497
Volltext / DOI:
doi:10.1089/wound.2022.0074
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36424821
Print-ISSN:
2162-1918
TUM Einrichtung:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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