User: Guest  Login
Title:

Noncoding RNA Transcripts during Differentiation of Induced Pluripotent Stem Cells into Hepatocytes.

Document type:
Journal Article
Author(s):
Skrzypczyk, Aniela; Kehr, Stephanie; Krystel, Ilona; Bernhart, Stephan H; Giri, Shibashish; Bader, Augustinus; Stadler, Peter F
Abstract:
Recent advances in the stem cell field allow to obtain many human tissues in vitro. However, hepatic differentiation of induced pluripotent stem cells (iPSCs) still remains challenging. Hepatocyte-like cells (HLCs) obtained after differentiation resemble more fetal liver hepatocytes. MicroRNAs (miRNA) play an important role in the differentiation process. Here, we analysed noncoding RNA profiles from the last stages of differentiation and compare them to hepatocytes. Our results show that HLCs m...     »
Journal title abbreviation:
Stem Cells Int
Year:
2018
Journal volume:
2018
Pages contribution:
5692840
Language:
eng
Fulltext / DOI:
doi:10.1155/2018/5692840
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30210551
Print-ISSN:
1687-966X
TUM Institution:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
 BibTeX