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Titel:

Assessment of cardiovascular risk of new drugs for the treatment of diabetes mellitus: risk assessment vs. risk aversion.

Dokumenttyp:
Journal Article; Review
Autor(en):
Zannad, Faiez; Stough, Wendy Gattis; Lipicky, Raymond J; Tamargo, Juan; Bakris, George L; Borer, Jeffrey S; Alonso García, Maria de Los Angeles; Hadjadj, Samy; Koenig, Wolfgang; Kupfer, Stuart; McCullough, Peter A; Mosenzon, Ofri; Pocock, Stuart; Scheen, André J; Sourij, Harald; Van der Schueren, Bart; Stahre, Christina; White, William B; Calvo, Gonzalo
Abstract:
The Food and Drug Administration issued guidance for evaluating the cardiovascular risk of new diabetes mellitus drugs in 2008. Accumulating evidence from several completed trials conducted within this framework raises questions as to whether requiring safety outcome studies for all new diabetes mellitus therapies remains justified. Given the burden of cardiovascular disease in patients with diabetes, the focus should shift towards cardiovascular outcome studies designed to evaluate efficacy (i....     »
Zeitschriftentitel:
Eur Heart J Cardiovasc Pharmacother
Jahr:
2016
Band / Volume:
2
Heft / Issue:
3
Seitenangaben Beitrag:
200-5
Sprache:
eng
Volltext / DOI:
doi:10.1093/ehjcvp/pvw007
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27418973
Print-ISSN:
2055-6837
TUM Einrichtung:
Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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