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Title:

Myosin binding protein H-like (MYBPHL): a promising biomarker to predict atrial damage.

Document type:
Journal Article
Author(s):
Lahm, Harald; Dreßen, Martina; Beck, Nicole; Doppler, Stefanie; Deutsch, Marcus-André; Matsushima, Shunsuke; Neb, Irina; König, Karl Christian; Sideris, Konstantinos; Voss, Stefanie; Eschenbach, Lena; Puluca, Nazan; Deisenhofer, Isabel; Doll, Sophia; Holdenrieder, Stefan; Mann, Matthias; Lange, Rüdiger; Krane, Markus
Abstract:
Myosin binding protein H-like (MYBPHL) is a protein associated with myofilament structures in atrial tissue. The protein exists in two isoforms that share an identical amino acid sequence except for a deletion of 23 amino acids in isoform 2. In this study, MYBPHL was found to be expressed preferentially in atrial tissue. The expression of isoform 2 was almost exclusively restricted to the atria and barely detectable in the ventricle, arteria mammaria interna, and skeletal muscle. After atrial da...     »
Journal title abbreviation:
Sci Rep
Year:
2019
Journal volume:
9
Journal issue:
1
Fulltext / DOI:
doi:10.1038/s41598-019-46123-w
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31292467
Print-ISSN:
2045-2322
TUM Institution:
Institut für Laboratoriumsmedizin (keine SAP-Zuordnung!); Klinik für Herz- und Gefäßchirurgie (Prof. Lange)
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