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Title:

A stochastic reaction-diffusion modeling investigation of FLASH ultra-high dose rate response in different tissues

Document type:
Article
Author(s):
Abolfath, Ramin; Baikalov, Alexander; Fraile, Alberto; Bartzsch, Stefan; Schueler, Emil; Mohan, Radhe
Abstract:
Purpose: The aim of the study was to propose a theory based on topology and geometry of diffusion channels in tissue to contribute to the mechanistic understanding of normal tissue sparing at ultra-high dose rates (UHDRs) and explore an interplay between intra- and inter-track radical recombination through a reaction-diffusion mechanism.Methods: We calculate the time evolution of particle track structures using a system of coupled reaction-diffusion equations on a random network designed for mol...     »
Journal title abbreviation:
Front. Physics
Year:
2023
Journal volume:
11
Fulltext / DOI:
doi:10.3389/fphy.2023.1060910
Print-ISSN:
2296-424X
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie (Prof. Combs)
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