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Titel:

Combination of Photon and Carbon Ion Irradiation with Targeted Therapy Substances Temsirolimus and Gemcitabine in Hepatocellular Carcinoma Cell Lines.

Dokumenttyp:
Journal Article; Article
Autor(en):
Dehne, Sarah; Fritz, Clarissa; Rieken, Stefan; Baris, Daniela; Brons, Stephan; Haberer, Thomas; Debus, Jürgen; Weber, Klaus-Josef; Schmid, Thomas E; Combs, Stephanie E; Habermehl, Daniel
Abstract:
This work investigates on putative cytotoxic effects in four different hepatocellular carcinoma (HCC) cell lines after irradiation with photons or carbon ions in combination with new targeted molecular therapy using either Temsirolimus (TEM) or Gemcitabine (GEM).The HCC cell lines HepG2, Hep3B, HuH7, and PLC were cultured and irradiated with photons or carbon ions at the Heidelberg Ion Beam Therapy Center using the raster-scanning method. For combination experiments, cell lines were first treate...     »
Zeitschriftentitel:
Front Oncol
Jahr:
2017
Band / Volume:
7
Seitenangaben Beitrag:
35
Sprache:
eng
Volltext / DOI:
doi:10.3389/fonc.2017.00035
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28348976
Print-ISSN:
2234-943X
TUM Einrichtung:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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