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Title:

Efficacy and toxicity of bimodal radiotherapy in WHO grade 2 meningiomas following subtotal resection with carbon ion boost: Prospective phase 2 MARCIE trial.

Document type:
Journal Article
Author(s):
Deng, Maximilian Y; Maas, Sybren L N; Hinz, Felix; Karger, Christian P; Sievers, Philipp; Eichkorn, Tanja; Meixner, Eva; Hoegen-Sassmannshausen, Philipp; Hörner-Rieber, Juliane; Lischalk, Jonathan W; Seidensaal, Katharina; Bernhardt, Denise; Jungk, Christine; Unterberg, Andreas; Wick, Antje; Wick, Wolfgang; von Deimling, Andreas; Sahm, Felix; Combs, Stephanie; Herfarth, Klaus; Debus, Jürgen; König, Laila
Abstract:
BACKGROUND: Novel radiotherapeutic modalities using carbon ions provide an increased relative biological effectiveness (RBE) compared to photons, delivering a higher biological dose while reducing radiation exposure for adjacent organs. This prospective phase 2 trial investigated bimodal radiotherapy using photons with carbon-ion (C12)-boost in patients with WHO grade 2 meningiomas following subtotal resection (Simpson grade 4 or 5). METHODS: A total of 33 patients were enrolled from July 2012 u...     »
Journal title abbreviation:
Neuro-oncol
Year:
2024
Journal volume:
26
Journal issue:
4
Pages contribution:
701-712
Fulltext / DOI:
doi:10.1093/neuonc/noad244
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/38079455
Print-ISSN:
1522-8517
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie (Prof. Combs)
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