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Title:

Survival of patients with ruptured gastrointestinal stromal tumour treated with adjuvant imatinib in a randomised trial.

Document type:
Article; Early Access; Journal Article; Randomized Controlled Trial
Author(s):
Joensuu, Heikki; Reichardt, Annette; Eriksson, Mikael; Hohenberger, Peter; Boye, Kjetil; Cameron, Silke; Lindner, Lars H; Jost, Philipp J; Bauer, Sebastian; Schütte, Jochen; Lindskog, Stefan; Kallio, Raija; Jaakkola, Panu M; Goplen, Dorota; Wardelmann, Eva; Reichardt, Peter
Abstract:
BACKGROUND: Patients with ruptured gastrointestinal stromal tumour (GIST) have poor prognosis. Little information is available about how adjuvant imatinib influences survival. METHODS: We explored recurrence-free survival (RFS) and overall survival (OS) of patients with ruptured GIST who participated in a randomised trial (SSG XVIII/AIO), where 400 patients with high-risk GIST were allocated to adjuvant imatinib for either 1 year or 3 years after surgery. Of the 358 patients with confirmed local...     »
Journal title abbreviation:
Br J Cancer
Year:
2024
Journal volume:
131
Journal issue:
2
Pages contribution:
299-304
Fulltext / DOI:
doi:10.1038/s41416-024-02738-z
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/38862742
Print-ISSN:
0007-0920
TUM Institution:
Klinik und Poliklinik für Innere Medizin III, Hämatologie und Onkologie (Prof. Bassermann)
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