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Title:

Side Effects of CXC-Chemokine Receptor 4-Directed Endoradiotherapy with Pentixather Before Hematopoietic Stem Cell Transplantation.

Document type:
Article; Journal Article
Author(s):
Maurer, Sabine; Herhaus, Peter; Lippenmeyer, Romina; Hänscheid, Heribert; Kircher, Malte; Schirbel, Andreas; Maurer, H Carlo; Buck, Andreas K; Wester, Hans-Jürgen; Einsele, Hermann; Grigoleit, Götz-Ulrich; Keller, Ulrich; Lapa, Constantin
Abstract:
The chemokine receptor CXC-chemokine receptor 4 (CXCR4) is a transmembrane receptor involved in survival, proliferation, and dissemination of different cancers, including hematopoietic malignancies. Relapsed or refractory hematopoietic cancers are frequently resistant to conventional therapy, and novel highly active strategies are urgently needed. CXCR4-directed endoradiotherapy constitutes a highly promising targeted therapeutic concept. Here, we investigated the adverse effects of this novel t...     »
Journal title abbreviation:
J Nucl Med
Year:
2019
Journal volume:
60
Journal issue:
10
Pages contribution:
1399-1405
Fulltext / DOI:
doi:10.2967/jnumed.118.223420
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30850502
Print-ISSN:
0161-5505
TUM Institution:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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