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Title:

Intranasal oxytocin reduces provoked symptoms in female patients with posttraumatic stress disorder despite exerting sympathomimetic and positive chronotropic effects in a randomized controlled trial.

Document type:
Journal Article; Randomized Controlled Trial
Author(s):
Sack, M; Spieler, D; Wizelman, L; Epple, G; Stich, J; Zaba, M; Schmidt, U
Abstract:
Posttraumatic stress disorder (PTSD) is a severe psychiatric disease accompanied by neuroendocrine changes such as adrenergic overdrive and hence an elevated cardiovascular morbidity. Current pharmacotherapeutic options for PTSD are less than suboptimal, necessitating the development of PTSD-specific drugs. Although the neuropeptide oxytocin has been repeatedly suggested to be effective in PTSD treatment, there are, to our knowledge, only three studies that have assessed its efficacy on the inte...     »
Journal title abbreviation:
BMC Med
Year:
2017
Journal volume:
15
Journal issue:
1
Pages contribution:
40
Language:
eng
Fulltext / DOI:
doi:10.1186/s12916-017-0801-0
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28209155
Print-ISSN:
1741-7015
TUM Institution:
Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie
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