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Titel:

Opioids for chronic osteoarthritis pain: An updated systematic review and meta-analysis of efficacy, tolerability and safety in randomized placebo-controlled studies of at least 4 weeks double-blind duration.

Dokumenttyp:
Journal Article; Review; Review; Early Access
Autor(en):
Welsch, Patrick; Petzke, Frank; Klose, Petra; Häuser, Winfried
Abstract:
This updated systematic review evaluated the efficacy and safety of opioids compared with placebo for chronic osteoarthritis pain.Clinicaltrials.gov, CENTRAL, MEDLINE and PsycINFO were searched from October 2013 to July 2019. Randomized controlled trials comparing opioids with placebo and at least 4 weeks double-blinded duration were analysed. Primary outcomes were pain relief of 50% or greater, disability, tolerability and safety. Effects were summarized by a random effects model using risk dif...     »
Zeitschriftentitel:
Eur J Pain
Jahr:
2020
Band / Volume:
24
Heft / Issue:
4
Seitenangaben Beitrag:
685-703
Volltext / DOI:
doi:10.1002/ejp.1522
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31876347
Print-ISSN:
1090-3801
TUM Einrichtung:
Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie
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