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Title:

Vascular Repair by Circumferential Cell Therapy Using Magnetic Nanoparticles and Tailored Magnets.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Journal Article
Author(s):
Vosen, Sarah; Rieck, Sarah; Heidsieck, Alexandra; Mykhaylyk, Olga; Zimmermann, Katrin; Bloch, Wilhelm; Eberbeck, Dietmar; Plank, Christian; Gleich, Bernhard; Pfeifer, Alexander; Fleischmann, Bernd K; Wenzel, Daniela
Abstract:
Cardiovascular disease is often caused by endothelial cell (EC) dysfunction and atherosclerotic plaque formation at predilection sites. Also surgical procedures of plaque removal cause irreversible damage to the EC layer, inducing impairment of vascular function and restenosis. In the current study we have examined a potentially curative approach by radially symmetric re-endothelialization of vessels after their mechanical denudation. For this purpose a combination of nanotechnology with gene an...     »
Journal title abbreviation:
ACS Nano
Year:
2016
Journal volume:
10
Journal issue:
1
Pages contribution:
369-76
Language:
eng
Fulltext / DOI:
doi:10.1021/acsnano.5b04996
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26736067
Print-ISSN:
1936-0851
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung
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