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Titel:

Magnetofection Enhances Adenoviral Vector-based Gene Delivery in Skeletal Muscle Cells.

Dokumenttyp:
Journal Article
Autor(en):
Pereyra, Andrea Soledad; Mykhaylyk, Olga; Lockhart, Eugenia Falomir; Taylor, Jackson Richard; Delbono, Osvaldo; Goya, Rodolfo Gustavo; Plank, Christian; Hereñu, Claudia Beatriz
Abstract:
The goal of magnetic field-assisted gene transfer is to enhance internalization of exogenous nucleic acids by association with magnetic nanoparticles (MNPs). This technique named magnetofection is particularly useful in difficult-to-transfect cells. It is well known that human, mouse, and rat skeletal muscle cells suffer a maturation-dependent loss of susceptibility to Recombinant Adenoviral vector (RAd) uptake. In postnatal, fully differentiated myofibers, the expression of the primary Coxsacki...     »
Zeitschriftentitel:
J Nanomed Nanotechnol
Jahr:
2016
Band / Volume:
7
Heft / Issue:
2
Sprache:
eng
Volltext / DOI:
doi:10.4172/2157-7439.1000364
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27274908
TUM Einrichtung:
Institut für Experimentelle Onkologie und Therapieforschung
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