User: Guest  Login
Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Harder, Ina; Münchhalfen, Matthias; Andrieux, Geoffroy; Boerries, Melanie; Grimbacher, Bodo; Eibel, Hermann; Maccari, Maria Elena; Ehl, Stephan; Wienands, Jürgen; Jellusova, Julia; Warnatz, Klaus; Keller, Baerbel
Title:
Dysregulated PI3K Signaling in B Cells of CVID Patients.
Abstract:
The altered wiring of signaling pathways downstream of antigen receptors of T and B cells contributes to the dysregulation of the adaptive immune system, potentially causing immunodeficiency and autoimmunity. In humans, the investigation of such complex systems benefits from nature's experiments in patients with genetically defined primary immunodeficiencies. Disturbed B-cell receptor (BCR) signaling in a subgroup of common variable immunodeficiency (CVID) patients with immune dysregulation and...     »
Journal title abbreviation:
Cells
Year:
2022
Journal volume:
11
Journal issue:
3
Fulltext / DOI:
doi:10.3390/cells11030464
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/35159274
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie
 BibTeX