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Title:

Robust Preanalytical Performance of Soluble PD-1, PD-L1 and PD-L2 Assessed by Sensitive ELISAs in Blood.

Document type:
Journal Article
Author(s):
Krueger, Kimberly; Mayer, Zsuzsanna; Kottmaier, Marc; Gerckens, Miriam; Boeck, Stefan; Luppa, Peter; Holdenrieder, Stefan
Abstract:
The interaction between programmed death-1 receptor PD-1 and its ligands PD-L1 and PD-L2 is involved in self-tolerance, immune escape of cancer, cardiovascular diseases, and COVID-19. As blood-based protein markers they bear great potential to improve oncoimmunology research and monitoring of anti-cancer immunotherapy. A variety of preanalytical conditions were tested to assure high quality plasma sample measurements: (i) different time intervals and storage temperatures before and after blood c...     »
Journal title abbreviation:
Biomedicines
Year:
2022
Journal volume:
10
Journal issue:
10
Fulltext / DOI:
doi:10.3390/biomedicines10102534
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/36289796
TUM Institution:
608; Institut für Klinische Chemie und Pathobiochemie
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