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Title:

An integrated device for fast and sensitive immunosuppressant detection.

Document type:
Article; Journal Article
Author(s):
Tombelli, Sara; Trono, Cosimo; Berneschi, Simone; Berrettoni, Chiara; Giannetti, Ambra; Bernini, Romeo; Persichetti, Gianluca; Testa, Genni; Orellana, Guillermo; Salis, Francesca; Weber, Susanne; Luppa, Peter B; Porro, Giampiero; Quarto, Giovanna; Schubert, Markus; Berner, Marcel; Freitas, Paulo P; Cardoso, Susana; Franco, Fernando; Silverio, Vânia; Lopez-Martinez, Maria; Hilbig, Urs; Freudenberger, Kathrin; Gauglitz, Günter; Becker, Holger; Gärtner, Claudia; O'Connell, Mark T; Baldini, Francesc...     »
Abstract:
The present paper describes a compact point of care (POC) optical device for therapeutic drug monitoring (TDM). The core of the device is a disposable plastic chip where an immunoassay for the determination of immunosuppressants takes place. The chip is designed in order to have ten parallel microchannels allowing the simultaneous detection of more than one analyte with replicate measurements. The device is equipped with a microfluidic system, which provides sample mixing with the necessary chem...     »
Journal title abbreviation:
Anal Bioanal Chem
Year:
2022
Journal volume:
414
Journal issue:
10
Pages contribution:
3243-3255
Fulltext / DOI:
doi:10.1007/s00216-021-03847-x
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/34936009
Print-ISSN:
1618-2642
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie
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