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Titel:

Dynamics of serum concentrations of antibodies to infliximab: a new approach for predicting secondary loss of response in inflammatory bowel diseases.

Dokumenttyp:
Journal Article
Autor(en):
Grasmeier, Melina K; Langmann, Anna F; Langmann, Peter; Treiber, Matthias; Thaler, Markus A; Luppa, Peter B
Abstract:
BACKGROUND: Antibodies to infliximab (ATI) in serum are associated with secondary loss of response (LOR) to infliximab (IFX) therapy in patients with inflammatory bowel disease (IBD). However, feasible ATI-related predictors of therapy success are lacking and knowledge about individual ATI dynamics is limited. Therefore, this study analyzed whether ATI dynamics are able to predict LOR to IFX therapy and compared their predictive power with known predictors of LOR to IFX. METHODS: This was a retr...     »
Zeitschriftentitel:
Therap Adv Gastroenterol
Jahr:
2021
Band / Volume:
14
Volltext / DOI:
doi:10.1177/17562848211037849
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34434255
Print-ISSN:
1756-283X
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); Institut für Klinische Chemie und Pathobiochemie
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