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Titel:

B-cell lymphoma/leukaemia 10 and angiotensin II-induced kidney injury.

Dokumenttyp:
Journal Article
Autor(en):
Markó, Lajos; Park, Joon-Keun; Henke, Norbert; Rong, Song; Balogh, András; Klamer, Samuel; Bartolomaeus, Hendrik; Wilck, Nicola; Ruland, Jürgen; Forslund, Sofia K; Luft, Friedrich C; Dechend, Ralf; Müller, Dominik N
Abstract:
AIMS: B-cell lymphoma/leukaemia 10 (Bcl10) is a member of the CARMA-Bcl10-MALT1 signalosome, linking angiotensin (Ang) II, and antigen-dependent immune-cell activation to nuclear factor kappa-B signalling. We showed earlier that Bcl10 plays a role in Ang II-induced cardiac fibrosis and remodelling, independent of blood pressure. We now investigated the role of Bcl10 in Ang II-induced renal damage. METHODS AND RESULTS: Bcl10 knockout mice (Bcl10 KO) and wild-type (WT) controls were given 1% NaCl...     »
Zeitschriftentitel:
Cardiovasc Res
Jahr:
2020
Band / Volume:
116
Heft / Issue:
5
Seitenangaben Beitrag:
1059-1070
Volltext / DOI:
doi:10.1093/cvr/cvz169
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31241148
Print-ISSN:
0008-6363
TUM Einrichtung:
Institut für Klinische Chemie und Pathobiochemie
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